Endocrine Abstracts

Background /aim: Osteoporosis is a generalized bone disease, characterized by impaired bone firmness, resulting in an increased predisposition for fractures. In order to detect the subjects at risk for fractures, one should actively search for them, primarily in a group of postmenopausal women, considering clinical risk factors. Apart from others, the relevant risk factors are lack of estrogen and low body mass index (BMI <19 kg/m2).: The aim of this study was t...

Sixteen percent of parathyroid adenomas can be situated in an ectopic location. Ectopic parathyroid glands result from aberrant migration during early stages of development, and lack of successful identification may lead to lack of success in parathyroid surgery. These glands are most frequently found in the anterior mediastinum, in association with the thymus or the thyroid gland. Ectopic parathyroid glands are a major cause of persistent and recurrent hyperparathyroidism.</p...

Background: The partial or complete hypopituitarism is described as late complication of hemorrhagic fever with renal syndrome (HFRS). Imaging methods of pituitary gland examination in the chronic phase showed pituitary atrophy, but a precise pathogenic mechanism that causes pituitary damage in HRFS remains unclear. While hypopituitarism in HFRS is rarely described, cardiac failure as a known complication of hypopituitarism is even more rarely described. We present a case of s...

Introduction: Secondary failure (SF) to treatment with oral therapy is defined as the absence of a favorable reaction to the oral therapy which was effective in the previous course of the treatment. The aim of the work was to investigate the acute effects of the short-term insulin therapy on the secretory ability of endocrine pancreatic beta cells and the insulin resistance. Materials and Methods: 98 patients with diabetes mellitus type 2 (DM T2) and confirmed the SF to the or...

Introduction: Clinical assessment of atherosclerotic complications in type 2 diabetes mellitus (DM) was diverted to the detection of subclinical form of atherosclerosis using the non-invasive diagnostic methods. Surrogate markers of subclinical atherosclerosis are carotid intima-media thickness (IMT) and albuminuria. The aim of this study was to analyze a relationship between the presence of albuminuria and carotid IMT in patients with type 2 DM and silent ischemia.<p clas...

IntroductionDiabetes mellitus (DM) is considered as equivalent to cardiovascular disease (CVD), so the intensive control of all risk factors for CVD in patients with DM is recommended. Risk factors for CVD include: dyslipidemia, hypertension, smoking, family history of CVD and albuminuria. In addition to being a sensitive and reliable marker for evaluation of kidney function, research suggests that cystatin C may be a useful predictor for the detection a...

Septooptic dysplasia is a clinically heterogeneous disorder characterized by optic nerve hypoplasia, pituitary hormone abnormalities and midline brain defects.clinical diagnosis requires the presence of at least two of the features of the classical triad. Here is male presented on endocrinology consult for the first time at the age of thirthy five. On clinical examination height and weight were normal, face hypogonadal, sparced facial and body hair, testicle hypotrophy, normoc...

Introduction: The diagnostic criteria of polycystic ovary syndrome (PCOS) are still under discussion and the hormonal parameters, including anti-Mullerian hormone range and hyperandrogenism, are not determined. Serum AMH level has been proposed as a surrogate marker for PCOM and could, therefore, be integrated in the diagnostic classifications for PCOS\. The aim of the present study was to characterize hormonal features of PCOS and to establish the most important hormonal para...